Mouse SF-20/IL-25

产品描述

onocyte colony-stimulating factor (M-CSF, CSF-1) is a macrophage lineage-specific growth factor. Full length human M-CSF transcripts encode a 522 amino acid (aa) type I transmembrane (TM) protein with a 464 aa extracellular region, a 21 aa TM domain, and a 37 aa cytoplasmic tail that forms a 140 kDa covalent dimer. The first 223 aa of mature human M-CSF shares 88%, 86%, 81% and 74% aa identity with corresponding regions of dog, cow, mouse and rat MCSF, respectively. M-CSF Induces vascular endothelial growth factor production and angiogenic activity from human monocytes. Whatmore, M-CSF and GM-CSF are mediators involved in regulating the numbers and function of macrophage lineage populations and have been shown to contribute to macrophage heterogeneity. 

 

产品参数

别名(Synonyms)

IL-17E, IL-25, MYDGF

Accession

Q9CPT4

GeneID

28106

表达系统(Source)

E.coli-derived Mouse SF-20/IL-25, Val25-Leu166, with an N-terminal Met.

分子量大小(Molecular Weight)

Approximately 15.8 kDa.

氨基酸序列(AA Sequence)

MVSEPTTVPF DVRPGGVVHS FSQDVGPGNK FTCTFTYASQ GGTNEQWQMS LGTSEDSQHF TCTIWRPQGK SYLYFTQFKA ELRGAEIEYA MAYSKAAFER ESDVPLKSEE FEVTKTAVSH RPGAFKAELS KLVIVAKAAR SEL

标签(Tag)

None

外观(Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

纯度(Purity)

> 95% by SDS-PAGE and HPLC analyses.

生物活性(Biological Activity)

Data Not Available.

内毒素(Endotoxin)

< 1.0 EU per 1μg of the protein by the LAL method.

制剂(Formulation)

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

复溶(Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.

 

储存条件

产品用冰袋装运,可在-20℃至-80℃下保存1年。

建议第一次使用时将蛋白质分成较小的量,并避免反复冻融循环。

 

注意事项

1.避免反复冻融循环。

2.为了您的安全和健康,请穿实验服,戴一次性手套进行操作。

3.仅供研究使用!

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